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Fragile X shows drug trial tribulations

May 23, 2014 - USA TODAY

Four years ago when drug trials started, families dealing with the genetic disease Fragile X were filled with optimism.

For the first time, they had hope that their loved ones might get a break from the anxiety, agitation, and communication and cognitive problems of Fragile X. Perhaps they'd even be able to learn.

Upbeat stories trickled out. Teenagers were able to hold their first real conversation. Boys stopped hitting themselves and knocking their heads against walls. Families wer...