Assembly Biosciences, Inc.

Assembly Biosciences, Inc.

Assembly Biosciences, Inc.

Overview
Date Founded

2005

Headquarters

331 Oyster Point Boulevard,4th floor,South San Francisco, CA 94080

Type of Company

Public

Employees (Worldwide)

115

Industries

Pharmaceuticals
Hospitals & Patient Services
Biotechnology

Company Description

Assembly Biosciences, Inc. is a biotechnology company, which engages in the development of products for infectious diseases, such as chronic hepatitis B virus and illnesses associated with a dysbiotic microbiome. It focuses in two innovative platform programs: oral therapeutics for the treatment of hepatitis B virus, and the oral synthetic live biotherapeutics candidate. The company was founded by Uri Lopatin and Derek A. Small on October 7, 2005 and is headquartered in South San Francisco, CA.

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Executives & Employees

Co-Founder

Chief Executive Officer & President, Director

Chief Financial & Accounting Officer

General Counsel, Senior Vice President of Legal Operations, Corporate Secretary

Executive Vice President & Chief Scientific Officer of Virology Operations

Senior Vice President, Chief Scientific Officer Microbiome

Chief Medical Officer

Co-Head, Microbiome Program

Senior Vice President-Corporate Development & Strategy

Senior Vice President, Investor Relations & Corporate Affairs

Board of Directors

Interim Chief Executive Officer & Chairman of the Board at Five Prime Therapeutics, Inc.

Co-Founder at Assembly Biosciences, Inc.

Chief Executive Officer & President, Director at Assembly Biosciences, Inc.

Chief Financial Officer at Biotix, Inc.

Co-Founder at Batu Biologics, Inc.

Director, President & Chief Executive Officer at Citius Pharmaceuticals, Inc.

Co-Founder at Indiana Proteomics Consortium LLC

Former Chief Financial Officer at Central Lewmar LP

Former President at Eli Lilly & Company

Former Chief Business Officer at NGM Biopharmaceuticals, Inc.

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Assembly Biosciences, Inc.
Owners & Shareholders
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Ecor1 Capital manages the EcoR1 Capital Fund LP, a fundamental long/short equity hedge fund focusing on investment opportunities in the biotechnology sector. The firm employs an innovative, process-driven approach that is based on a value philosophy which attempts to manage risk in the volatile biotechnology sector. The fund focuses on outliers not typically analyzed as part of value based diligence; human capital in addition to deep scientific and financial analysis. Ecor1 Capital is committed to going beyond the usual monetary investment in companies and engages directly with management to identify opportunities for efficiencies and growth, and where necessary, invests their own human capital resources to help mediate much of the risk that is inherent in the sector. The goal of combining this innovative perspective and process is generation of uncorrelated returns relative to the biotechnology sector and to the overall market.

Details Hidden

Consonance Capital Management's (CCM) funds seek to deliver exceptional, uncorrelated risk adjusted returns. CCM seeks to meet this objective by focusing on investment opportunities in the publicly traded stocks of healthcare companies. The firm invests in all sub-sectors of the healthcare sector including healthcare information technology, managed care, pharmaceuticals, specialty pharmaceuticals, commercial stage biotechnology, healthcare facilities and services, medical devices and supplies, diagnostics and consumer-based healthcare companies.CCM believes the public healthcare market lends itself to an active long/short strategy. The firm focuses on creating long and short portfolios driven by the opportunity for absolute return and alpha creation. The funds also invest in other types of securities and may use a variety of investment techniques to generate profit and/or control risk. These may include participating in swaps, buying or selling futures contracts, purchasing and writing options and other derivative contracts, purchasing or selling debt instruments, and trading on margin by borrowing funds and pledging securities as collateral. CCM invests primarily in healthcare companies in the US, and on an opportunistic basis in the rest of the world.^

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RSCM applies a research-intensive, fundamental approach to investing the funds across multiple healthcare subsectors, with a focus on allocating capital to the highest conviction ideas. The firm's investment process leverages a long-term horizon, seeking to take advantage of the healthcare sector's inherent volatility to increase position sizes over time. The funds RSCM provides investment advisory services to are permitted to make a limited amount of investments in private companies and may make investments in companies outside of healthcare-related industries, as the firm determines to be appropriate for the funds' overall portfolio balance and long-term investment strategy.

Recent Transactions
Details Hidden

Assembly Biosciences, Inc. issued USD Common Stock

Details Hidden

Assembly Biosciences, Inc. issued USD Common Stock

Details Hidden

Assembly Biosciences, Inc. issued USD Common Stock

Transaction Advisors
Escrow Agent

Advised onAssembly Biosciences, Inc. issued USD Common Stock

Underwriter

Advised onAssembly Biosciences, Inc. issued USD Common Stock

Legal Advisor

Advised on issued USD Common Stock

Managing Director

Advised onAssembly Biosciences, Inc. issued USD Common Stock

Chair, Life Sciences Practice

Advised onAssembly Biosciences, Inc. issued USD Common Stock

Professional

Advised onAssembly Biosciences, Inc. issued USD Common Stock

Advisors & Consultants
Advisor

Co-Founder at Assembly Biosciences, Inc.

Scientific Advisor

Visiting Partner at Y Combinator LLC

Consultant

Former Chief Scientific Officer & Head of the Microbiome Program at Assembly Biosciences, Inc.

Clients

Allergan Plc engages in the research, development, and manufacture of pharmaceutical products. It operates through the following business segments: US Specialized Therapeutics; US General Medicine, and International. The US Specialized Therapeutics segment includes sales and expenses relating to branded products within the United States. The US General Medicine segment involves Central Nervous System; Gastrointestinal; Women's Health; Anti-Infectives; and Diversified brands. The International segment comprises of products sold outside the United States. The company was founded in 1984 and is headquartered in Dublin, Ireland.

Key Stats and Financials As of 2019
Market Capitalization
$476M
Total Enterprise Value
$275M
Earnings Per Share
$-3.72
Revenue
$16M
Net Profit
$-97.6M
EBITDA
$-100M
EBITDAMargin
-627.19%
Total Debt
$12.3M
Total Equity
$273M
Enterprise Value Sales
17.26x
TEVNet Income
-2.82x
Debt TEV
0.04x
Suppliers
Indiana University Bloomington, INDIANA

Indiana University is a major multi-campus public research institution, grounded in the liberal arts and sciences, and a world leader in professional, medical, and technological education. Indiana University’s mission is to provide broad access to undergraduate, graduate, and continuing education for students throughout Indiana, the United States, and the world, as well as outstanding academic and cultural programs and student services. Indiana University seeks to create dynamic partnerships with the state and local communities in economic, social, and cultural development and to offer leadership in creative solutions for 21st century problems. Indiana University strives to achieve full diversity, and to maintain friendly, collegial, and humane environments, with a strong commitment to academic freedom.

Competitors
Johnson & Johnson Pharmaceuticals - New Brunswick, New Jersey

Johnson & Johnson is a holding company, which engages in the research and development, manufacture and sale of products in the health care field. It operates through the following segments: Consumer, Pharmaceutical, and Medical Devices. The Consumer segment includes products used in the baby care, oral care, beauty, over-the-counter pharmaceutical, women's health, and wound care markets. The Pharmaceutical segment focuses on therapeutic areas such as immunology, infectious diseases ad vaccines, neuroscience, oncology, cardiovascular and metabolism, and pulmonary hypertension. The Medical Devices segment offers products used in the orthopedic, surgery, cardiovascular, diabetes care, and eye health fields. The company was founded by Robert Wood Johnson I, James Wood Johnson and Edward Mead Johnson Sr. in 1886 and is headquartered in New Brunswick, NJ.

Roche Holding AG Pharmaceuticals - Basel, Switzerland

Roche Holding ag Roche Personalised Healthcare – our mission The healthcare landscape is constantly changing. Patients, physicians and payers demand safer, more effective treatments, while investors search after robust and sustainable business models. Growing demand for highly effective, impactful medicines is being driven by an aging population, healthcare and economic pressures. But an influx of new technologies enables Roche to meet this need by offering innovative tests and medicines. These healthcare drivers have led us in one direction – ‘Roche Personalised Healthcare’. At Roche, ‘Personalised Healthcare’ is at the core of our business strategy

Gilead Sciences, Inc. Biotechnology - Foster City, CA

Since 1987, Gilead Sciences has worked to discover, develop and commercialize medications to advance the care of patients suffering from life-threatening diseases in areas of unmet medical need. In 25 years, Gilead has become a leading biopharmaceutical company with a portfolio of 15 marketed products, a growing pipeline of investigational drugs and approximately 5,000 employees in offices across four continents. Gilead's therapeutic areas of focus include HIV/AIDS, hepatitis, serious respiratory, cardiovascular, and metabolic conditions, cancer and inflammation

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